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Search Results for " programmed cell death 1 "

ターゲット

阻害剤

1775

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T12379	PD-1-IN-22		Others , PD-1/PD-L1
	PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).		Others , PD-1/PD-L1
T9907	Nivolumab		PD-1/PD-L1
	Nivolumab (anti-PD-1) is a genetically engineered fully human immunoglobulin Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed death-1PD-1PCD-1) with immune ...		PD-1/PD-L1
T83970	IMMH 010 maleate	YPD-30 maleate	PD-1/PD-L1
	IMMH 010 maleate (YPD-30 maleate) is an orally available programmed cell death ligand 1 inhibitor with potential antitumor activity for the study of neurological disorders and advanced malignant solid tumors.		PD-1/PD-L1
T76750	Cemiplimab	REGN-2810,SAR-439684	Others
	Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody against programmed cell death receptor 1 (PD-1) and a checkpoint inhibitor that blocks PD-1/PD-L1 mediated T-cell inhibition and can be used in metastatic cance...		Others
T40111L	BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride		PD-1/PD-L1
	BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride is a resorcinol di-Ph ether scaffold-based programmed cell death-1 (PD-1)/programmed cell death ligand 1 (PD-L1) inhibitor that inhibits the PD-1/PD-L1 interaction wi...		PD-1/PD-L1
T12387	PD1-PDL1-IN 1		Others
	PD1-PDL1-IN 1 is a potent inhibitor of programmed cell death 1 (PD-1),and used as immune modulator.		Others
T70291	PCC0208018
	PCC0208018 is a novel activator of effector T cells, enhancing T cell proliferation and activation to release interferon gamma (IFN-γ) and interleukin-2 (IL-2) without blocking the programmed cell death 1 (PD-1)/programm...
T12377L	PD-1-IN-17 (TFA) (1673560-66-1 free base)	PD-1-IN-17 (TFA)	Others
	PD-1-IN-17 TFA is a inhibitor of programmed cell death-1 (PD-1) .		Others
T61750	Anticancer agent 72
	Anticancer agent 72 (compound 8c) effectively inhibits the K+ channel, displaying significant potential as an anticancer treatment. Additionally, it induces apoptosis, a programmed cell death process [1].
T73630	PD1-PDL1-IN 1 TFA
	PD1-PDL1-IN 1 TFA (compound 16) is a potent inhibitor of programmed cell death 1 (PD-1), functioning as an immune modulator [1].
T36047	LH1307
	LH1307 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 3 nM in a homologous time-resolved fluorescence (HTRF) assay.1 It increases the activation o...
T80052	Cathepsin B
	Cathepsin B, a cysteine protease, plays a role in various forms of programmed cell death, such as apoptosis, pyroptosis, ferroptosis, necroptosis, and autophagic cell death [1].
T63256	PD-1-IN-17 TFA
	PD-1-IN-17 TFA is a potent inhibitor of programmed cell death-1 (PD-1), inhibiting 92% of splenocyte proliferation at a concentration of 100 nM.
T77180	Retifanlimab
	Retifanlimab, an anti-programmed cell death protein 1 (anti-PD-1) monoclonal antibody (mAb), is utilized in the research of gastroesophageal adenocarcinoma (GEA) [1].
T77178	Pucotenlimab
	Pucotenlimab (HX008), a humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting programmed cell death protein 1 (anti-PD-1), serves as a potential agent in tumor research [1].
T36046	LH1306
	LH1306 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 25 nM in a homologous time-resolved fluorescence (HTRF) assay.1 It increases the activation ...
T12377	PD-1-IN-17		PD-1/PD-L1
	PD-1-IN-17 is an inhibitor of programmed cell death-1 (PD-1). PD-1-IN-17 inhibits 92% splenocyte proliferation at 100 nM.		PD-1/PD-L1
T81928	Lipustobart		PD-1/PD-L1
	Lipustobart is an IgG4-kappa humanized monoclonal antibody targeting PDCD1 (programmed cell death 1, PD1, PD-1, CD279), with immunostimulant and antineoplastic activity [1].		PD-1/PD-L1
T76714	Sugemalimab
	Sugemalimab, a fully human, full-length, IgG4 monoclonal antibody (mAb) targeting programmed death ligand 1 (PD-L1), exhibits anticancer activities and is applicable in non-small cell lung cancer research [1].
T60776	Anticancer agent 68
	Compound 12, also known as Anticancer agent 68, functions as an anti-cancer agent by arresting cells at the G2/M phase and inducing programmed cell death. Moreover, it promotes tumor suppression by activating p53 and PTE...
T76936	Budigalimab
	Budigalimab (ABBV 181; PR 1648817), a humanized IgG1 monoclonal antibody, specifically targets the programmed cell death 1 (PD-1) receptor. It features an Fc mutation to decrease interactions with the Fc receptor, thereb...
T80588	Bintrafusp alfa	M7824,MSB0011359C
	Bintrafusp alfa (M 7824), a pioneering bifunctional fusion protein, integrates the extracellular domain of TGF-βRII with a human IgG1 monoclonal antibody that inhibits the programmed cell death ligand. This compound is u...
TP1947	P110
	Dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity. Displays no effect on dynamin 1 or other mitochondrial dynamics-related proteins. Inhibits mitochondrial fission, dysfunction and reactive oxygen...
T36034	CAY10774
	CAY10774 is an inhibitor of the protein-protein interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 (IC50= 15 nM in a homologous time-resolved fret (HTRF) assay).1It increases the activation of Jurkat...
T82508	Eciskafusp alfa		PD-1/PD-L1
	Eciskafusp alfa, a cis-targeted IL2v immunocytokine, acts on programmed cell death 1 (PDCD1, commonly known as PD-1), preferentially targeting antigen-specific stem-like PD-1+ TCF-1+ CD8+ T cells to differentiate into a ...		PD-1/PD-L1
T83724	TPP-1 hydrochloride	Targeting PD-L1 Peptide
	TPP-1, a peptide inhibitor, targets the interaction between programmed cell death protein 1 (PD-1) and its ligand (PD-L1), binding specifically to PD-L1 with a dissociation constant (Kd) of 94.67 nM. At a concentration o...

Compounds

PD-1-IN-22

T12379

Synonym:

Target: Others, PD-1/PD-L1

Synonym: YPD-30 maleate

Target: PD-1/PD-L1

Cemiplimab

T76750

Synonym: REGN-2810,SAR-439684

Target: Others

BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride

PD-1-IN-17 (TFA) (1673560-66-1 free base)

T12377L

Synonym: PD-1-IN-17 (TFA)

Synonym: M7824,MSB0011359C

Synonym: Targeting PD-L1 Peptide

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04342	PD-1 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	PD-1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.7 kDa and the accession number is XP_022265285.1.
TMPY-05260	PD-1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	PD-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is B0LAJ3.
TMPY-05815	PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated	Canine	HEK293 Cells
	PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 19.41 kDa and the accession number is A0A090BAM7.
TMPY-00996	PD-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	PD-1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.6 kDa and the accession number is Q02242.
TMPY-05395	PD-1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	PD-1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.9 kDa and the accession number is Q02242.
TMPY-04898	PD-1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	PD-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number is A0A0M3M0G7.
TMPY-00897	PD-1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	PD-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is A0A0M3M0G7.
TMPY-05079	PD-1 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	PD-1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42.3 kDa and the accession number is A0A0M3M0G7.
TMPY-05827	PD-L2 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 48.93 kDa and the accession number is Q9BQ51-1.
TMPY-04346	PD-L2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-04957	PD-L2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-00250	PD-1 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293 Cells
	PD-1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.3 kDa and the accession number is A0A8J8XRF6.
TMPY-03717	PD-1 Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	PD-1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.2 kDa and the accession number is A6JR44.
TMPY-00633	PD-1 Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293 Cells
	PD-1 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number is A0A8J8XRF6.
TMPY-00253	PD-1 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	PD-1 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number is B0LAJ3.
TMPY-04341	PD-1 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	PD-1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.7 kDa and the accession number is A6JR44.
TMPY-00233	PD-1 Protein, Canine, Recombinant (hFc)	Canine	HEK293 Cells
	PD-1 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43 kDa and the accession number is XP_543338.3.
TMPY-05295	PD-1 Protein, Cynomolgus, Recombinant (hFc & Avi), Biotinylated	Cynomolgus	HEK293 Cells
	PD-1 Protein, Cynomolgus, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 44.5 kDa and the accession number is B0LAJ3.
TMPY-03738	PD-L2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	PD-L2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is A4GW30.
TMPY-03404	PD-L2 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	PD-L2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.6 kDa and the accession number is A4GW30.
TMPY-06838	PD-L2 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293 Cells
	PD-L2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is NP_001077068.1.
TMPY-06819	PD-L2 Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293 Cells
	PD-L2 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.6 kDa and the accession number is A4GW30.
TMPY-04225	PD-L2 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	PD-L2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.9 kDa and the accession number is D4AAV6.
TMPY-04223	PD-L2 Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	PD-L2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.2 kDa and the accession number is D4AAV6.
TMPY-04967	PD-1 Protein, Mouse, Recombinant (His), Biotinylated	Mouse	HEK293 Cells
	PD-1 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.6 kDa and the accession number is Q02242.
TMPJ-00181	PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell pr...
TMPY-05282	PD-L2 Protein, Mouse, Recombinant (His), Biotinylated	Mouse	HEK293 Cells
	PD-L2 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9WUL5.
TMPY-02436	PD-L2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	PD-L2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.5 kDa and the accession number is Q9WUL5.
TMPY-02352	PD-L2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	PD-L2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9WUL5.
TMPJ-00182	PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
	PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 70-95 KDa and the accession number is Q9NZQ7.
TMPJ-00183	PD-L1 Protein, Human, Recombinant (Flag)	Human	HEK293 Cells
	PD-L1 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with C-Flag tag. The predicted molecular weight is 35-40 KDa and the accession number is Q9NZQ7.
TMPJ-00718	AIF Protein, Human, Recombinant (His)	Human	E. coli
	Apoptosis-Inducing Factor 1, Mitochondrial (AIFM1) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. During apoptosis, it is t...
TMPY-05619	PD-1 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	PD-1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is A0A0M3M0G7.
TMPY-06336	PD-1 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
	PD-1 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 44.49 kDa and the accession number is NP_005009.2.
TMPY-00896	PD-1 Protein, Human, Recombinant (His & hFc)	Human	HEK293 Cells
	PD-1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 43.84 kDa and the accession number is A0A0M3M0G7.
TMPY-06682	PD-1 Protein, Human, Recombinant (Asp26-Pro39 deletion, His)	Human	HEK293 Cells
	PD-1 Protein, Human, Recombinant (Asp26-Pro39 deletion, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.65 kDa and the accession number is NP_005009.2.
TMPJ-00661	PDCD5 Protein, Human, Recombinant (His)	Human	E. coli
	Programmed Cell Death Protein 5 (PDCD5) is a member of the PDCD5 family. PDCD5 is expressed in tumor cells during apoptosis, independent of apoptosis-inducing stimuli. This protein may function in the process of apoptosi...
TMPJ-00638	PD-L1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	PD-L1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 32-40 KDa and the accession number is G7PSE7.
TMPY-06281	PD-L2 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 51.09 kDa and the accession number is Q9BQ51-1.
TMPJ-00637	PD-L1 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	PD-L1 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 73 KDa and the accession number is G7PSE7.
TMPY-00120	PD-L2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.3 kDa and the accession number is Q9BQ51-1.
TMPY-05613	PD-L2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 25.8 kDa and the accession number is Q9BQ51-1.
TMPJ-01300	PDCD10 Protein, Human, Recombinant	Human	E. coli
	Programmed Cell Death Protein 10 (PDCD10) belongs to the PDCD10 family. PDCD10 exists as a homodimer and is widely expressed. PDCD10 can increase mitogen-activated protein kinase activity and MST4 activity. PDCD10 is req...
TMPK-00584	BTN2A2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Butyrophilin (BTN) genes encode a set of related proteins. Cell surface BTN2A2 protein, such as the B7 family molecule programmed death ligand 1, was upregulated upon activation of T cells.BTN2A2 is a co-inhibitory molec...
TMPK-00180	PD-1 Protein, Human, Recombinant (aa 25-167, hFc & Avi), Biotinylated	Human	HEK293 Cells
	Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the ...
TMPK-00688	PD-1 Protein, Canine, Recombinant (aa 25-170, hFc)	Canine	HEK293 Cells
	Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the ...
TMPK-00181	PD-1 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated	Mouse	HEK293 Cells
	Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the ...
TMPY-02555	VSTM1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	V-set and transmembrane domain containing 1 (VSTM1) is a protein containing the V-set domains. V-set domains are immunoglobulin-like domains resembling the antibody variable region. V-set domains are found in many kinds ...
TMPY-01176	CIAP1 Protein, Human, Recombinant (Avi)	Human	E. coli
	The cellular inhibitor of apoptosis protein-1 (cIAP1) is a member of the Inhibitor of Apoptosis family proteins are (IAP) whose members are characterized by a novel domain of about 70 amino acids termed baculoviral IAP r...
TMPY-02563	VSTM1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	V-set and transmembrane domain containing 1 (VSTM1) is a protein containing the V-set domains. V-set domains are immunoglobulin-like domains resembling the antibody variable region. V-set domains are found in many kinds ...
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